Givlaari (givosiran)

Liver disease can be cause by a variety of things including infection (hepatitis), diseases, for example, gallstones, high cholesterol or triglycerides, blood flow obstruction to the liver, and toxins (medications and chemicals). Symptoms of liver disease depends upon the cause and may include nausea, vomiting, upper right abdominal pain, and jaundice. Treatment depends upon the cause of the liver disease.

Cirrhosis of the liver refers to a disease in which normal liver cells are replaced by scar tissue caused by alcohol and viral hepatitis B and C. This disease leads to abnormalities in the liver's ability to handle toxins and blood flow, causing internal bleeding, kidney failure, mental confusion, coma, body fluid accumulation, and frequent infections. Symptoms include yellowing of the skin (jaundice), itching, and fatigue. The prognosis is good for some people with cirrhosis of the liver, and the survival can be up to 12 years; however, the life expectancy is about 6 months to 2 years for people with severe cirrhosis with major complications.

Tylenol liver damage (acetaminophen) can occur from accidentally ingesting too much acetaminophen, or intentionally. Signs and symptoms of acetaminophen-induced liver damage may include nausea, vomiting, kidney failure, bleeding disorders, coma, and death. Acetaminophen is a drug contained in over 200 OTC and prescription medications from NyQuil to Vicodin. Avoiding unintentional overdoses includes reading medication labels, writing down the dosages of medications you are taking, do not drink excessive alcohol while taking acetaminophen. In severe cases, a liver transplant may be necessary.

What is liver pain after drinking alcohol? Learn the signs of liver disease and what to do if you have a painful liver after drinking alcohol. Qualifying as an alcoholic means having a mental and physical dependence on alcohol. Here are the symptoms and signs of alcoholism.

The liver is the largest gland and organ in the body. There are a variety of liver diseases caused by liver inflammation, scarring of the liver, infection of the liver, gallstones, cancer, toxins, genetic diseases, and blood flow problems. Symptoms of liver disease generally do not occur until the liver disease is advanced. Some symptoms of liver disease include jaundice, nausea and vomiting, easy bruising, bleeding excessively, fatigue, weakness, weight loss, shortness of breath, leg swelling, impotence, and confusion. Treatment of diseases of the liver depends on the cause.

Nonalcoholic fatty liver disease or NASH occurs due to the accumulation of abnormal amounts of fat within the liver. Fatty liver most likely caused by obesity and diabetes. Symptoms of fatty liver disease are primarily the complications of cirrhosis of the liver; and may include mental changes, liver cancer, the accumulation of fluid in the body (ascites, edema), and gastrointestinal bleeding. Treatment for fatty liver includes avoiding certain foods and alcohol. Exercise, weight loss, bariatric surgery, and liver transplantation are treatments for fatty liver disease.

Drug-induced liver diseases are diseases of the liver that are caused by physician-prescribed medications, OTC medications, vitamins, hormones, herbs, illicit (recreational) drugs, and environmental toxins. Read about the signs and symptoms of drug-induced liver disease like hepatitis (inflammation of the liver cells), liver disease treatment, and types.

Liver cancer is cancer of the liver cells (hepatocellular carcinoma) or of the ducts in the liver (cholangiocarcinoma). Liver cancer often arises due to liver damage, cirrhosis (scarring) caused by alcohol use/abuse, hepatitis B, or hepatitis C. Liver cancer may not cause any symptoms. Liver cancer is diagnosed with blood tests, imaging tests, and a liver biopsy. Treatment for liver cancer may include surgery, ablation, embolization, radiation, chemotherapy, and targeted therapy.

Liver pain can be a sign that you have a serious health problem like cirrhosis or liver cancer. Find out more about what could be causing your liver pain and how to treat it. Patients may have worsening symptoms of chronic liver disease or cirrhosis, which often precedes the development of cancer of the liver.

Liver transplant (LT) simply means replacing a diseased liver with a healthy one. The new liver may be taken from a brain-dead person (cadaver) or given by a living relative.

Because the liver is the only organ in the body that regenerates, or grows back, a transplanted segment of the liver can grow to a normal size within a few months. Liver transplantation is a surgical procedure performed to remove a diseased or injured liver from one person and replace it with a whole or portion of a healthy liver from another person called a donor.

No, liver hemangioma doesn’t go away without treatment. People who have liver hemangioma rarely experience signs and symptoms and typically don't need treatment. They are generally small and even if they become large they may not carry significant risk.

The liver is a vital organ regulating the levels of many substances in the body. It excretes a substance called bile. The bile helps in carrying away the waste from the liver. The blood from the digestive system (stomach and bowel) passes through the liver.

Your body spent months preparing to give birth, and you’ve gone through a lot of physical and emotional stress during both pregnancy and delivery. It makes sense that after your baby’s arrival, your body needs time to heal and recover.

Patients suffering from liver cancer usually complain of a throbbing or stabbing sensation in the upper right side of the abdomen or the back of the shoulder. There may or may not be a swelling that doesn’t subside. The pain may be severe; it is graded 7/10 in intensity. Some patients may not have any symptoms in the early stages of liver cancer.

Liver cancer is not detected by blood tests alone. Certain substances present in the blood called the blood markers may be elevated in patients with liver cancer. Raised levels of a tumor marker called alpha fetoprotein (AFP) can indicate diseases of the liver, including liver cancer.

A liver transplant is a surgical procedure performed to remove a damaged or failed liver and replace it with a healthy liver. Liver transplant is usually only performed for severe, end-stage chronic liver disease, which can no longer be treated by other treatment options.

Liver cirrhosis results from disease- or chemical-induced injury to the liver over a sustained period. The injury kills liver cells, and your body attempts to rebuild the damage. In the process, the existing cells are inflamed and scar tissue results, compromising the structure of the liver and hampering its function.

Liver cancer may not cause any signs or symptoms in its initial stages. When the cancer begins to show its signs and symptoms, you may feel pain in the abdomen, particularly at the top right.

A liver biopsy is a safe and quick procedure that takes around five minutes to complete. You may, however, be asked to lie on the bed for two hours after the procedure and take it easy for the next 24 hours.